Chemical ontologies: what are they, what are they for and what are the challenges

Ontologies encode human knowledge in computationally accessible forms. They are designed to narrow the gap between the knowledge of human experts and the functionality available in computer systems, by expressing expert knowledge in a manner computers can manipulate and reason over. With the ever-growing deluge of data in modern scientific domains, researchers need intelligent tools able to fil...

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Dendritic Spines: What Are They? What Are They For?

machinery is also identified in spines, within specialized subdomains (88, 102). In addition, polyribosomes and protein translational machinery are often anchored at the base of spines (80). Thus increasing evidence suggests that individual spines represent partially autonomous compartments, having their own regulated membrane-trafficking events that shuttle components into and out of the spine...

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Current information technology practices in neuroscience make it difficult to understand the organization of the brain across spatial scales. Subcellular junctional connectivity, cytoarchitectural local connectivity, and long-range topographical connectivity are just a few of the relevant data domains that must be synthesized in order to make sense of the brain. However, due to the heterogeneit...

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Ontologies for neuroscience : what are they and what are they good for ? Stephen

Current information technology practices in neuroscience make it difficult to understand the organization of the brain across spatial scales. Subcellular junctional connectivity, cytoarchitectural local connectivity, and long-range topographical connectivity are just a few of the relevant data domains that must be synthesized in order to make sense of the brain. However, due to the heterogeneit...

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Chemical ontologies: what are they, what are they for and what are the challenges

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